Compare the2025 Acura MDXVS 2025 Toyota Sequoia

In a Vehicle-to-Vehicle Frontal Crash Prevention 2.0 test conducted by the Insurance Institute for Highway Safety (IIHS), the Acura MDX achieved a “Acceptable” rating - the second highest possible - for its performance in forward collision warning and automatic braking systems, demonstrating its excellent capabilities in preventing collisions. The Toyota Sequoia has not been tested.

Full-time four-wheel drive is optional on the MDX. Full-time four-wheel drive gives added traction for safety in all conditions, not just off-road, like the only system available on the Sequoia.

For better protection of the passenger compartment, the MDX uses safety cell construction with a three-dimensional high-strength frame that surrounds the passenger compartment. It provides extra impact protection and a sturdy mounting location for door hardware and side impact beams. The Sequoia uses a body-on-frame design, which has no frame members above the floor of the vehicle.

Both the MDX and the Sequoia have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available around view monitors.

The Acura MDX achieved a “Top Safety Pick” rating from the Insurance Institute for Highway Safety (IIHS) for the 2025 model year. This recognition was based on its impressive performance in the small overlap frontal crash test, updated moderate overlap front crash test, updated side impact crash test, headlight evaluations, and pedestrian crash prevention testing. The Sequoia has not yet been evaluated by the IIHS for 2025.

The MDX comes with a full 4-year/50,000-mile basic warranty, which covers the entire truck and includes 24-hour roadside assistance. The Sequoia’s 3-year/36,000-mile basic warranty expires 1 year or 14,000 miles sooner.

Acura’s powertrain warranty covers the MDX 1 year and 10,000 miles longer than Toyota covers the Sequoia. Any repair needed on the engine, transmission, axles, joints or driveshafts is fully covered for 6 years or 70,000 miles. Coverage on the Sequoia ends after only 5 years or 60,000 miles.

As tested in Car and Driver the MDX Type S 3.0 turbo V6 is faster than the Toyota Sequoia:

On the EPA test cycle the MDX 3.5 SOHC V6 SH-AWD gets better fuel mileage than the Sequoia 4x4 (19 city/25 hwy vs. 19 city/22 hwy).

An engine control system that can shut down some of the engine’s cylinders helps improve the MDX’s fuel efficiency. The Sequoia doesn’t offer a system that can shut down part of the engine.

Both the MDX and Sequoia have a standard automatic start/stop engine feature to stop unnecessary fuel waste and pollution at stoplights and heavy traffic. The MDX has a standard disable switch for the system, so a driver can keep the engine from shutting off when the vehicle stops temporarily.

To lower fuel costs and make buying fuel easier, the Acura MDX uses regular unleaded gasoline (premium recommended for maximum performance). The Sequoia requires premium, which can cost on average about 84.9 cents more per gallon.

The MDX has a standard cap-less fueling system. The fuel filler is automatically opened when the fuel nozzle is inserted and automatically closed when it’s removed. This eliminates the need to unscrew and replace the cap and it reduces fuel evaporation, which causes pollution. The Sequoia doesn’t offer a cap-less fueling system.

For better stopping power the MDX Type S’ front brake rotors are larger than those on the Sequoia:

The MDX stops much shorter than the Sequoia:

The MDX’s standard tires provide better handling because they have a lower 55 series profile (height to width ratio) that provides a stiffer sidewall than the Sequoia’s standard 70 series tires. The MDX Type S’ tires have a lower 40 series profile than the Sequoia Capstone’s 50 series tires.

For better ride, handling and brake cooling the MDX has standard 19-inch wheels. Smaller 18-inch wheels are standard on the Sequoia.

The MDX has a standard easy tire fill system. When inflating the tires, the vehicle’s integrated tire pressure sensors keep track of the pressure as the tires fill and tell the driver when the tires are inflated to the proper pressure. The Sequoia doesn’t offer vehicle monitored tire inflation.

Having a flat tire is dangerous, inconvenient and expensive. The self-sealing tires available on the MDX can automatically seal most punctures up to 3/16 of an inch, effectively preventing most flat tires. The Sequoia doesn’t offer self-sealing tires.

The MDX has standard front and rear stabilizer bars, which help keep the MDX flat and controlled during cornering. The Sequoia’s suspension doesn’t offer a rear stabilizer bar.

The MDX Type S handles at .87 G’s, while the Sequoia Capstone pulls only .76 G’s of cornering force in a Car and Driver skidpad test.

For greater off-road capability the MDX Type S has a greater minimum ground clearance than the Sequoia TRD Pro (9.4 vs. 9.1 inches), allowing the MDX to travel over rougher terrain without being stopped or damaged.

The Acura MDX may be more efficient, handle and accelerate better because it weighs about 1350 to 1400 pounds less than the Toyota Sequoia.

The MDX is 9.7 inches shorter than the Sequoia, making the MDX easier to handle, maneuver and park in tight spaces.

The MDX is 7.1 inches shorter in height than the Sequoia, making the MDX much easier to wash and garage and drive (lower center of gravity).

Unibody construction lowers the MDX’s center of gravity significantly without reducing ground clearance. This contributes to better on the road handling and better off-road performance and stability. In addition, unibody construction makes the chassis stiffer, improving handling and reducing squeaks and rattles. The Sequoia doesn’t use unibody construction, but a body-on-frame design.

The MDX uses computer-generated active noise cancellation to help remove annoying noise and vibration from the passenger compartment, especially at low frequencies. The Sequoia doesn’t offer active noise cancellation.

The MDX has .4 inches more front legroom and .6 inches more third row headroom than the Sequoia.

The MDX’s cargo area provides more volume than the Sequoia.

J.D. Power and Associates surveys of service recipients show that Acura service is better than Toyota. J.D. Power ranks Acura 6th in service department satisfaction (above the industry average). With a 27% lower rating, Toyota is ranked 24th.

Unlike the driver-only memory system in the Sequoia Limited/TRD Pro/1794/Platinum/Capstone, the MDX offers an optional passenger memory, so that when drivers switch, the memory setting adjusts the driver’s seat, steering wheel position and outside mirror angle and the front passenger seat also adjusts to the new passenger’s preset preferences.

The MDX’s standard speed-sensitive wipers speed up when the vehicle does, so that the driver doesn’t have to continually adjust the speed of the wipers. The Sequoia’s standard manually variable intermittent wipers have to be constantly adjusted.

Consumer Reports rated the MDX’s headlight performance “Very Good,” a higher rating than the Sequoia’s headlights, which were rated “Good.”

To quickly and conveniently keep personal devices charged without cables tangling and wearing out, the Acura MDX has a standard wireless phone charging system (Qi) in the center console. Wireless charging costs extra on the Sequoia and isn’t available on the Sequoia SR5.

Insurance will cost less for the MDX owner. The Complete Car Cost Guide estimates that insurance for the MDX will cost $3645 to $7545 less than the Sequoia over a five-year period.

Consumer Reports® recommends the Acura MDX, based on reliability, safety and performance. The Toyota Sequoia isn't recommended.

The Acura MDX outsold the Toyota Sequoia by 89% during 2024.